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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PRKAR2B
All Species:
25.76
Human Site:
Y120
Identified Species:
37.78
UniProt:
P31323
Number Species:
15
Phosphosite Substitution
Charge Score:
0.33
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P31323
NP_002727.2
418
46302
Y120
A
S
V
C
A
E
A
Y
N
P
D
E
E
E
D
Chimpanzee
Pan troglodytes
XP_001148361
477
52826
Y179
A
S
V
C
A
E
A
Y
N
P
D
E
E
E
D
Rhesus Macaque
Macaca mulatta
XP_001089109
461
51060
Y163
A
S
V
C
A
E
A
Y
N
P
D
E
E
E
D
Dog
Lupus familis
XP_849179
417
46163
Y119
A
S
V
C
A
E
A
Y
N
P
D
E
E
E
D
Cat
Felis silvestris
Mouse
Mus musculus
P31324
416
46149
Y118
A
S
V
C
A
E
A
Y
N
P
D
E
E
E
D
Rat
Rattus norvegicus
P12369
416
46104
Y118
A
S
V
C
A
E
A
Y
N
P
D
E
E
E
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509189
323
36258
L63
D
I
L
L
F
K
N
L
D
P
E
Q
M
S
Q
Chicken
Gallus gallus
Q5ZM91
382
43332
Y106
G
A
I
S
A
E
V
Y
T
E
E
D
A
A
S
Frog
Xenopus laevis
NP_001084637
402
45172
D111
Y
N
P
D
E
E
D
D
D
T
E
V
K
I
L
Zebra Danio
Brachydanio rerio
NP_001070838
397
44672
D110
N
P
D
D
D
E
E
D
S
E
P
R
V
V
H
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P81900
377
42730
D109
T
A
V
F
P
K
T
D
E
Q
R
A
R
L
V
Honey Bee
Apis mellifera
XP_392905
383
43849
L116
T
D
A
Q
R
E
R
L
A
D
S
I
K
H
I
Nematode Worm
Caenorhab. elegans
P30625
366
41449
D106
K
K
V
V
I
P
K
D
D
A
T
R
R
S
L
Sea Urchin
Strong. purpuratus
Q26619
369
41770
E107
L
V
Y
P
K
S
D
E
Q
R
A
R
L
T
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P07278
416
47201
T131
H
T
R
E
K
T
S
T
P
P
L
P
M
H
F
Red Bread Mold
Neurospora crassa
Q01386
385
42138
Q116
V
H
P
K
T
A
E
Q
L
E
R
L
K
K
A
Conservation
Percent
Protein Identity:
100
86.5
90
96.6
N.A.
97.1
96.8
N.A.
70.3
34.6
78.4
68.1
N.A.
44
47.6
31.8
50.9
Protein Similarity:
100
87.2
90.2
98
N.A.
98
98.5
N.A.
74.1
52.3
85.4
80.6
N.A.
64.1
63.8
50.9
66.5
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
6.6
20
6.6
6.6
N.A.
6.6
6.6
6.6
0
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
40
46.6
33.3
13.3
N.A.
20
13.3
13.3
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
33.9
36.8
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
51.9
51.4
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
0
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
20
13.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
38
13
7
0
44
7
38
0
7
7
7
7
7
7
7
% A
% Cys:
0
0
0
38
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
7
7
7
13
7
0
13
25
19
7
38
7
0
0
38
% D
% Glu:
0
0
0
7
7
63
13
7
7
19
19
38
38
38
7
% E
% Phe:
0
0
0
7
7
0
0
0
0
0
0
0
0
0
7
% F
% Gly:
7
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
7
7
0
0
0
0
0
0
0
0
0
0
0
13
7
% H
% Ile:
0
7
7
0
7
0
0
0
0
0
0
7
0
7
7
% I
% Lys:
7
7
0
7
13
13
7
0
0
0
0
0
19
7
0
% K
% Leu:
7
0
7
7
0
0
0
13
7
0
7
7
7
7
13
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
13
0
0
% M
% Asn:
7
7
0
0
0
0
7
0
38
0
0
0
0
0
0
% N
% Pro:
0
7
13
7
7
7
0
0
7
50
7
7
0
0
0
% P
% Gln:
0
0
0
7
0
0
0
7
7
7
0
7
0
0
7
% Q
% Arg:
0
0
7
0
7
0
7
0
0
7
13
19
13
0
0
% R
% Ser:
0
38
0
7
0
7
7
0
7
0
7
0
0
13
7
% S
% Thr:
13
7
0
0
7
7
7
7
7
7
7
0
0
7
0
% T
% Val:
7
7
50
7
0
0
7
0
0
0
0
7
7
7
7
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
7
0
7
0
0
0
0
44
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _